Recombinant Noggin Proteins
5 products
Background
Noggin is a key growth factor inhibitory protein that belongs to the bone morphogenetic protein family and has diverse biological functions. Its name "noggin" is derived from the English slang meaning "head" because the protein is crucial for the formation of the nervous and skeletal systems during embryonic development.
The main function of Noggin is to regulate the development of bones and nervous system by inhibiting the activity of bone morphogenetic proteins. During embryonic development, Noggin promotes the differentiation of embryonic primitive cells into various tissue cells, such as nerve cells and cartilage cells, by blocking the signaling of bone morphogenetic proteins. This is essential for the proper formation of the head and limbs.
In addition to its role in development, Noggin also plays an important regulatory role in adult organisms. Noggin's balancing role is critical to maintaining bone health during osteoblast differentiation and bone diseases. In addition, Noggin is also widely used in stem cell research, and its inhibitory effect helps control the directionality of stem cell differentiation.
Resources
Noggin Proteins Blog Articles
Featured Products
| Cat. No. | Species | Product Description | Host | Structure | Purity | Activity | Features |
|---|---|---|---|---|---|---|---|
| BLPSN-3536 | Human | Human Noggin Protein (His Tag), Active | Mammalian cell | Q13253 (1-232aa) | > 95 % | ED50: 0.05-0.3 μg/mL | SDS-PAGE,Cell Based |
| BL-0027NP | Human | Human Noggin Protein (C-Fc) | Mammalian cell | Q13253 (28-232aa) | > 95 % | Not Test | SDS-PAGE |
| BLPSN-3534 | Human | Human Noggin Protein, Active | Mammalian cell | Q13253 (1-232aa) | > 95 % | ED50: 10-80 ng/mL. | SDS-PAGE,Cell Based,HPLC |
| BL-2253NP | Human | Human Noggin Protein, Active | Mammalian cell | Q13253 (28-232aa) | > 95 % | ED50: 0.2 μg/mL | SDS-PAGE,Cell Based,HPLC |
| Human | Human Noggin Protein, Active | Mammalian cell | Q13253 (28-232aa) | > 90 % | ED50: 2.0-3.0 ng/ml | SDS-PAGE,Cell Based | |
| BL-0001NP | Mouse | Mouse Noggin Protein (C-6His), Active | Mammalian cell | P97466 (28-232aa) | > 95 % | The organoids showed good morphology and germination rate. | SDS-PAGE,Cell Based,HPLC |
