Recombinant Hepatocyte Growth Factor (HGF) Proteins

12 products

Background

Hepatocyte Growth Factor (HGF) is a multifunctional cytokine protein that is widely involved in biological processes such as cell growth, differentiation, and migration. HGF was originally discovered to have the ability to proliferate and regenerate liver cells, hence its name. However, its effects are not limited to the liver but play important roles in multiple tissues and organs.

HGF initiates complex signaling pathways mainly by binding to its receptor, c-Met (a tyrosine kinase receptor).  This results in the activation of multiple signaling molecules within the cell, thereby regulating cell survival, proliferation, and migration. Under normal physiological conditions, HGF plays a key role in tissue repair and regeneration, especially during injury and wound healing.

Abnormal expression of HGF is associated with a variety of diseases, including cancer, inflammatory diseases, and tissue fibrosis. In cancer, excessive activation of the HGF/c-Met signaling pathway is closely related to tumor occurrence, development, and metastasis. Therefore, HGF has become an important research object in cancer treatment research.


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Featured Products

Cat. No. Species Product Description Host Structure Purity Activity Features
BLC-05961P Human Human HGF Protein (His), Active Mammalian cell P14210 (32-728aa) ≥ 95 % ED50: ≤10 ng/ml. SDS-PAGE
BL-0311NP Human Human HGF Protein (C-6His), Active Mammalian cell P14210 (32-728aa) ≥ 95 % ED50: 0.3-1.5 ng/ml. SDS-PAGE,Cell Based,HPLC,BLI
BLPSN-2428 Human Human HGF Protein, Active Mammalian cell P14210 (1-728aa) ≥ 95 % ED50: 0.2-2 ng/mL. SDS-PAGE,Cell Based
Human Human HGF Protein, Active Mammalian cell P14210 (32-728aa) ≥ 90 % ED50: ≤20 ng/mL. SDS-PAGE,Cell Based
BL-1219NP Mouse Mouse HGF Protein (C-6His) Mammalian cell Q08048 (33-728aa) ≥ 95 % Not Test SDS-PAGE
BLPSN-2430 Mouse Mouse HGF Protein (His Tag), Active Mammalian cell Q08048 (1-728aa) > 70 % ED50: 1-8 ng/mL. SDS-PAGE
BLPSN-2429 Mouse Mouse HGF Protein, Active Mammalian cell Q08048 (1-728aa) ≥ 95 % ED50: 1-4 ng/ml. SDS-PAGE,Cell Based
BLPSN-2431 Rat Rat HGF Protein, Active Mammalian cell P17945 (1-728aa) ≥ 85 % ED50: 1-6 ng/mL. SDS-PAGE,Cell Based
BLC-02340P Rat Rat HGF Protein (GST) E.coli P17945 (477-728aa) ≥ 90 % Not Test SDS-PAGE
BLC-00450P Bovine Bovine HGF Protein (His) E.coli Q76BS1 (32-494aa) ≥ 85 % Not Test SDS-PAGE
BLC-07251P Bovine Bovine HGF Protein (His) E.coli Q76BS1 (32-494aa) ≥ 85 % Not Test SDS-PAGE
BLPSN-2427 Cynomolgus Cynomolgus HGF Protein, Active Mammalian cell C9E9X5 (1-728aa) ≥ 95 % ED50: 2-10 ng/mL. SDS-PAGE,Cell Based
BLPSN-2426 Canine Canine HGF Protein, Active Mammalian cell Q867B7 (1-730aa) ≥ 95 % ED50: 1-4 ng/mL. SDS-PAGE,Cell Based

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