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Recombinant Cynomolgus 4-1BB Protein (His Tag)

Cat No.: 41BB-0480NP
Cynomolgus CD137 Protein, Cynomolgus TNFRSF9 Recombinant
Description Related products
tag His
host species Cynomolgus
accession A9YYE7
synonym 4-1BB CD137; ILA; TNFRSF9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA
background 4-1BB (CD137; TNFRS9), an activation-induced costimulatory molecule, is an important regulator of immune responses. Targeting 4-1BB or its natural ligand 4-1BB ligand (4-1BBL) has important implications in many clinical conditions, including cancer. In-depth analysis revealed that 4-1BB-mediated anti-cancer effects are based on its ability to induce activation of cytotoxic T lymphocytes (CTL), and among others, high amounts of IFN-γ.
description Recombinant Cynomolgus 4-1BB ligand receptor is expressed by our expression system and the target gene encoding Leu24-Gln186 is expressed
source Human Cells
AA sequence Leu24-Gln186
purity >90% as determined by reducing SDS-PAGE.
endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
formulation Recombinant Cynomolgus 4-1BB Protein was lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
reconstitution Dissolve the lyophilized protein in distilled water.
usage For Research Use Only
storage Cynomolgus 4-1BB protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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