Recombinant Mouse HDAC5 Protein
Beta LifeScience
SKU/CAT #: BL-0236SG
Recombinant Mouse HDAC5 Protein
Beta LifeScience
SKU/CAT #: BL-0236SG
Catalog No.: BL-0236SG
Product Overview
| Tag | GST |
| Host Species | Mouse |
| Accession | BC060609 |
| Synonym | mHDA1; AI426555; mKIAA0600 |
| Background | HDAC5 or Histone deacetylase 5 belongs to the class II histone deacetylase/acuc/apha family that possesses histone deacetylase activity and represses transcription when tethered to a promoter (1). HDAC 5 plays a critical role in transcriptional regulation, cell cycle progression, and developmental events and also acts as a potential therapeutic target for the prevention of atherosclerosis. HDAC5 can co-immunoprecipitates with HDAC3 family members forming multicomplex proteins. HDAC5 can also interact with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. HDAC5 gene is thought to be associated with colon cancer (2). |
| Description | Recombinant mouse HDAC5 (617-end) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods. This protein is purified with our unique purification methods. |
| Source | Sf9 insect cells |
| AA Sequence | 617a.a.-end |
| Molecular Weight | ~80 kDa |
| Purity | For specific purity information on a given lot, see related COA. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Active |
| Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| Stability | The recombinant protein is stable for up to 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Recombinant Mouse HDAC5 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
