Recombinant Human UBE2A Protein

Beta LifeScience SKU/CAT #: BL-0117SG
Recombinant Human UBE2A Protein

Recombinant Human UBE2A Protein

Beta LifeScience SKU/CAT #: BL-0117SG
Catalog No.: BL-0117SG

Product Overview

Tag His
Host Species Human
Accession NM_003336
Synonym HHR6A; MRXS30; MRXSN; RAD6A; UBC
Background UBE2A or ubiquitin-conjugating enzyme E2A is a member of the E2 ubiquitin-conjugating enzyme family which is required for post-replicative DNA damage repair and plays an important role in various cellular processes. RAD18 and RAD5 play a central role in mediating physical contacts between the members of the RAD6 pathway. UBE2A is specifically important during chronic low dose ultraviolet exposure to prevent counterproductive DNA checkpoint activation and allow cells to proliferate normally. Loss of the RAD6 error-free PRR pathway results in DNA damage checkpoint-induced G2 arrest in CLUV-exposed cells.
Description Recombinant full-length human UBE2A was produced in E. coli system, fused with a His tag at N-terminus.
Source E.coli
AA Sequence Full Length
Molecular Weight 17 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human UBE2A Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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