Recombinant Human UBE2A Protein
Beta LifeScience
SKU/CAT #: BL-0117SG
Recombinant Human UBE2A Protein
Beta LifeScience
SKU/CAT #: BL-0117SG
Catalog No.: BL-0117SG
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | NM_003336 |
| Synonym | HHR6A; MRXS30; MRXSN; RAD6A; UBC |
| Background | UBE2A or ubiquitin-conjugating enzyme E2A is a member of the E2 ubiquitin-conjugating enzyme family which is required for post-replicative DNA damage repair and plays an important role in various cellular processes. RAD18 and RAD5 play a central role in mediating physical contacts between the members of the RAD6 pathway. UBE2A is specifically important during chronic low dose ultraviolet exposure to prevent counterproductive DNA checkpoint activation and allow cells to proliferate normally. Loss of the RAD6 error-free PRR pathway results in DNA damage checkpoint-induced G2 arrest in CLUV-exposed cells. |
| Description | Recombinant full-length human UBE2A was produced in E. coli system, fused with a His tag at N-terminus. |
| Source | E.coli |
| AA Sequence | Full Length |
| Molecular Weight | 17 kDa |
| Purity | For specific purity information on a given lot, see related COA. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Active |
| Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| Stability | The recombinant protein is stable for up to 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Recombinant Human UBE2A Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
