Recombinant Human ODC1 Protein (C-6His, N-T7 tag)
Beta LifeScience
SKU/CAT #: BL-2067NP

BL-2067NP: Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Recombinant Human ODC1 Protein (C-6His, N-T7 tag)
Beta LifeScience
SKU/CAT #: BL-2067NP
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Human Ornithine Decarboxylase is produced by our E.coli expression system and the target gene encoding Met1-Val461 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus. |
Accession | P11926 |
Synonym | Ornithine decarboxylase; ODC1; |
Gene Background | Ornithine decarboxylase (ODC1) is an enzyme which belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC1 is the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. |
Molecular Mass | 53.5 KDa |
Apmol Mass | 25 &58 KDa, reducing conditions |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Purity | Greater than 90% as determined by reducing SDS-PAGE. (QC verified) |
Biological Activity | Not tested |
Reconstitution | |
Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Shipping | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Usage | For Research Use Only |
Target Details
Target Function | Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. |
Protein Families | Orn/Lys/Arg decarboxylase class-II family |
Database References | HGNC: 8109 OMIM: 165640 KEGG: hsa:4953 STRING: 9606.ENSP00000234111 UniGene: PMID: 28157137 |