Recombinant Human HRAS1 (Mature form) Protein

Beta LifeScience SKU/CAT #: BL-0179SG
Recombinant Human HRAS1 (Mature form) Protein

Recombinant Human HRAS1 (Mature form) Protein

Beta LifeScience SKU/CAT #: BL-0179SG
Catalog No.: BL-0179SG

Product Overview

Tag His
Host Species Human
Accession NM_005343
Synonym C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; HRAS; H-RASIDX; HAMSV; K-RAS; N-RAS; RASH1
Background The RAS gene superfamily encodes a group of closely related 21,000 dalton (p21) proteins with special affinity for guanine nucleotides (GTP). RAS and several other cellular proteins with similar biochemical properties are collectively known as G-proteins and they play key roles in a wide variety of cellular activities, including cell growth, differentiation, secretion, and protein trafficking (1). There are three forms of RAS gene in cells termed H-RAS, N-RAS, and K-RAS. RAS proteins play a direct causal role in human cancer and in other diseases. Mutant H-RAS, N-RAS, and K-RAS occur in varying frequencies in different tumor types (2). Other members of the RAS superfamily may also contribute to cancer.
Description Recombinant human RAS1 (2-186) was produced in E. coli, fused with a His tag at N-terminus.
Source E.coli
AA Sequence 2-186
Molecular Weight ~23 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human HRAS1 (Mature form) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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