Recombinant Human HRAS1 (Mature form) Protein
Beta LifeScience
SKU/CAT #: BL-0179SG
Recombinant Human HRAS1 (Mature form) Protein
Beta LifeScience
SKU/CAT #: BL-0179SG
Catalog No.: BL-0179SG
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | NM_005343 |
| Synonym | C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; HRAS; H-RASIDX; HAMSV; K-RAS; N-RAS; RASH1 |
| Background | The RAS gene superfamily encodes a group of closely related 21,000 dalton (p21) proteins with special affinity for guanine nucleotides (GTP). RAS and several other cellular proteins with similar biochemical properties are collectively known as G-proteins and they play key roles in a wide variety of cellular activities, including cell growth, differentiation, secretion, and protein trafficking (1). There are three forms of RAS gene in cells termed H-RAS, N-RAS, and K-RAS. RAS proteins play a direct causal role in human cancer and in other diseases. Mutant H-RAS, N-RAS, and K-RAS occur in varying frequencies in different tumor types (2). Other members of the RAS superfamily may also contribute to cancer. |
| Description | Recombinant human RAS1 (2-186) was produced in E. coli, fused with a His tag at N-terminus. |
| Source | E.coli |
| AA Sequence | 2-186 |
| Molecular Weight | ~23 kDa |
| Purity | For specific purity information on a given lot, see related COA. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Active |
| Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| Stability | The recombinant protein is stable for up to 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Recombinant Human HRAS1 (Mature form) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
