Production-Optimized Proteins
8944 products
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The Lab is Open. Your Research is Waiting.
Production Ready Proteins Starting at $445/100ug
High-Purity Recombinant Proteins for Research Use
The Production-Optimized Proteins collection is a curated line of recombinant proteins manufactured with an emphasis on affordability, scalability, and production consistency. Designed to meet the rigorous needs of research laboratories across academic, biotechnology, and pharmaceutical sectors, these proteins are expressed under optimized conditions that maximize yield while maintaining structural and functional integrity.
Each product in this collection is rigorously assessed for identity, purity, and integrity using standard biochemical techniques such as SDS-PAGE. The proteins are ideal for functional assays, method development, antibody validation, protein interaction studies, and other general research applications.
Collection Highlights
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High Expression Yields with Scalable Formats
All proteins in this collection are expressed under optimized systems (e.g., E. coli, CHO) that support high-yield production and consistent scalability from milligram to gram quantities. -
≥95% Purity Confirmed by SDS-PAGE
Each recombinant protein is purified via affinity or chromatography-based methods and validated for purity and integrity, typically exceeding 95%, ideal for downstream applications. -
Cost-Effective for Routine Research
Designed with affordability in mind, this collection offers economical options for labs requiring frequent access to quality proteins for standard research assays and exploratory studies. -
Ready-to-Use Formulation
Supplied in convenient buffer systems (e.g., PBS, Tris-HCl), proteins are ready for immediate use in ELISA, Western blotting, protein-protein interaction assays, or as assay standards. -
Flexible Application Range
Suitable for a broad spectrum of uses including antibody validation, enzymatic assays, pathway studies, binding kinetics, and custom protocol development.
🔬 Key Research Areas with Production-Optimized Protein Targets
Research Area |
Associated Diseases |
Protein Targets |
Role/Importance |
|---|---|---|---|
| Cancer Biology & Immuno-oncology | Breast, lung, colorectal, melanoma, etc. | PD-1, PD-L1, CTLA-4, VEGF, EGFR, HER2, p53, MDM2 | Targets involved in tumor immune evasion, growth signaling, or cell cycle control. |
| Inflammation & Autoimmunity | Rheumatoid arthritis, IBD, psoriasis, MS | TNF-α, IL-1β, IL-6, IL-17A, IL-23, IFN-γ, TGF-β | Cytokines that mediate chronic inflammation and autoimmunity. |
| Neuroscience & Neurodegeneration | Alzheimer’s, Parkinson’s, ALS, MS | BDNF, α-synuclein, tau, TREM2, ApoE, IL-1β | Biomarkers and mediators of neuroinflammation, synaptic plasticity, proteinopathy. |
| Metabolic Disease & Obesity | Type 2 diabetes, NAFLD, obesity, PCOS | Insulin, leptin, adiponectin, FGF21, IL-6 | Metabolic regulators and endocrine markers for insulin resistance and lipogenesis. |
| Infectious Disease & Vaccinology | COVID-19, HIV, HBV, TB, RSV, influenza | SARS-CoV-2 S protein, HIV gp120, IFN-α/β, IL-12, GM-CSF | Viral antigens and immunomodulators for vaccines or diagnostics. |
| Cardiovascular & Thrombosis | Atherosclerosis, stroke, thrombosis, hypertension | VCAM-1, ICAM-1, CRP, IL-6, VEGF, thrombin | Vascular inflammation markers, angiogenesis regulators, coagulation proteins. |
| Fibrosis & Wound Healing | Pulmonary fibrosis, liver fibrosis, skin injury | TGF-β, PDGF, CTGF, FGF2, MMP-9 | Key in fibroblast activation, ECM remodeling, and tissue repair. |
| Stem Cell & Regenerative Biology | Cell therapy, organoids, tissue engineering | FGF2, BMP4, Wnt3a, Activin A, Noggin, EGF | Used in differentiation and maintenance of stem cells and organoid models. |
| Diagnostics & Biomarkers | Oncology, inflammation, neurodegeneration | PSA, CRP, NSE, IL-6, GFAP, S100B | Protein biomarkers with diagnostic or prognostic significance. |
| Epigenetics & Cell Signaling | Cancer, development, immune evasion | HDACs, DNMTs, STAT3, JAK1, MAPK, AKT | Signaling transducers and transcriptional regulators. |
🔧 Semi-Custom Options Available
While our catalog proteins are optimized for standard expression and purification workflows, we understand that specific research objectives often demand tailored protein formats. To support these diverse needs, all proteins in the Production-Optimized Proteins collection are eligible for semi-custom manufacturing, offering researchers flexibility without the cost or time commitment of full custom development.
Our semi-custom services allow for adjustments to critical production parameters to better align with experimental requirements, assay compatibility, or downstream applications.
✅ Available Customization Options:
Customization Category |
Available Options |
Purpose / Benefit |
|---|---|---|
| Expression Host System |
|
- Obtain correct protein folding and post-translational modifications (PTMs) - Improve solubility and activity - Enhance compatibility with mammalian systems |
| Tag Type & Configuration |
|
- Simplify purification and detection - Enable structural or functional studies without interference - Allow tag removal post-purification for native protein |
| Buffer Composition |
|
- Enhance protein stability and shelf-life - Ensure compatibility with specific assays or storage systems - Prevent aggregation or denaturation |
| Endotoxin Reduction |
|
- Safe for use in cell-based assays or animal models - Required for immunology, vaccine, and inflammation research workflows |
| Concentration & Fill Volume |
|
- Minimize handling and avoid freeze-thaw cycles - Enable large-scale or high-throughput experiments - Optimize reagent usage for specific protocols |
| Isoform or Variant Selection |
|
- Investigate isoform-specific functions or interactions - Model disease mutations or post-translational variants - Assemble native complexes in vitro |
| Analytical Characterization |
|
- Confirm identity, purity, and size - Meet publication, grant, or regulatory requirements - Quality control for reproducibility and comparability |
