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| tag | His |
| host species | SARS |
| accession | AAX16193.1 |
| background | The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. |
| description | A DNA sequence encoding the SARS coronavirus (SARS-CoV) (strain WH20) papain-like protease (PLpro) (AAX16193.1) (Glu1541-Tyr1859) was expressed in E.coli and fused with a His tag at the C-terminus. |
| source | E.coli |
| predicted n terminal | Glu 1541 |
| AA sequence | Glu1541-Tyr1859 |
| molecular weight | The recombinant SARS coronavirus (SARS-CoV) (strain WH20) papain-like protease (PLpro) consists of 319 amino acids and predicts a molecular mass of 35.8 kDa. |
| purity | > 90% as determined by SDS-PAGE. |
| formulation | The recombinant SARS coronavirus (SARS-CoV) (strain WH20) papain-like protease (PLpro) was lyophilized from sterile 50 mM Tris, 0.1 % Tween, pH 9.0. |
| stability | The recombinant SARS coronavirus (SARS-CoV) (strain WH20) papain-like protease (PLpro) is stable for up to 1 year from date of receipt at -20℃ to -80℃. |
| usage | For Research Use Only |
| storage | Store the antigen under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
