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Recombinant Rat CD27 Protein (Fc Tag)

Cat No.: BLPSN-0844
Description Related products
tag Fc
host species Rat
accession NP_001019506.1
background CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has important role in generation of T cell immunity, and is an apparently robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD7 on lymphocytes and dendritic cells. The CD27-CD7 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.Immune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsCo-stimulatory Immune Checkpoint Targets ImmunotherapyCancer ImmunotherapyTargeted Therapy
description A DNA sequence encoding the rat CD27 (NP_001019506.1) (Met1-Arg183) was expressed with the Fc region of human IgG1 at the C-terminus.
source HEK293
predicted n terminal Thr 21
AA sequence Met1-Arg183
molecular weight The recombinant rat CD27 consists of 404 a.a. and predicts a molecular mass of 45 kDa.
purity >95% as determined by SDS-PAGE.
endotoxin < 1.0 EU per μg protein as determined by the LAL method.
bioactivity Please contact us for detailed information
formulation Lyophilized from sterile PBS, pH 7.4..
stability The recombinant proteins are stable for up to 1 year from date of receipt at -70℃.
usage For Research Use Only
storage Store the protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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