Recombinant Rat B7-H3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0321
Recombinant Rat B7-H3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0321
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Rat |
Accession | Q7TPB4 |
Synonym | B7-H3 CD276 antigen; CD276; B7 homolog 3; B7-H3;CD276 |
Background | CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20-27% amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature also correlates with poor survival in patients, suggesting that it may play a role in tumor cell migration. |
Description | A DNA sequence encoding the rat CD276 (Q7TPB4)(Met1-Phe244) was produced with a His tag at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Val 29 |
AA Sequence | Met1-Phe244 |
Molecular Weight | The recombinant rat CD276 comprises 227 amino acids and predicts a molecular mass of 25 kDa. The apparent molecular mass of the recombinant protein is approximately 43 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Purity | Greater than 95% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4 |
Stability | Recombinnat Proteins are stable for up to 1 year from date of receipt at -70°C |
Usage | For Research Use Only |
Storage | Store recombinant protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |