Recombinant Mouse LAG-3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3119
Recombinant Mouse LAG-3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3119
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Mouse |
Accession | NP_032505.1 |
Synonym | LAG-3 Lymphocyte activation gene 3 protein;LAG3;LAG-3;Protein FDC;CD223 |
Background | Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling. It can lead to increased antigen-specific T-cell responses in vivo. LAG-3 has higher affinity to MHC class II than CD4. |
Description | A DNA sequence encoding the mouse Lag3 (NP_032505.1) (Met1-Leu442) was produced with a His tag at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Ser 23 |
AA Sequence | Met1-Leu442 |
Molecular Weight | The recombinant mouse Lag3 consists 431 amino acids and predicts a molecular mass of 46.8 kDa. |
Purity | Greater than 95% as determined by SDS-PAGE. |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | Recombinnat Proteins are stable for up to 1 year from date of receipt at -70°C |
Usage | For Research Use Only |
Storage | Store recombinant protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |