Recombinant Mouse CD36 Protein
Beta LifeScience
SKU/CAT #: BL-0049PS
Recombinant Mouse CD36 Protein
Beta LifeScience
SKU/CAT #: BL-0049PS
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Mouse |
Synonym | Platelet glycoprotein 4, Glycoprotein IIIb, GPIIIB, PAS IV, PAS-4, Platelet glycoprotein IV, GPIV, CD36, Cd36. |
Background | Plateletglycoprotein IV, also known as CD36 is an integral membrane glycoprotein whichhas multiple physiological functions. CD36 is broadly expressed on a wide arrayof cell types. CD36 is part of the scavenger receptor family and acts as amultiligand pattern recognition receptor which interacts with a large number ofstructurally dissimilar ligands. Furthermore, CD36 participates in lipidmetabolism and has been known as a fatty acid translocase which is required forthe bindingas well as transport of LCFA in cells & tissues. CD36 also takes a major partin the initiation as well as pathogenesis of chronic inflammatory diseases suchas Alzheimer's disease and atherosclerosis. CD36 is an integral membraneprotein which mainly functions as a receptor for thrombospondin & collagen.CD36 directly mediates the cytoadherence of Plasmodium falciparum parasitizederythrocytes. |
Description | CD36 expressed in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 419a.a. (30-439a.a.) and having a molecular weight of 47.4kDa (Molecular size on SDS-PAGE will appear at approximately 57-70kDa).CD36 is expressed with a 6a.a. His tag at C-Terminus and purified by unique purification methods. |
Source | Sf9 |
AA Sequence | ADPGDMLIEK TIKREVVLEE GTTAFKNWVK TGTTVYRQFW IFDVQNPDDVAKNSSKIKVK QRGPYTYRVR YLAKENITQD PEDHTVSFVQ PNGAIFEPSL SVGTEDDNFT VLNLAVAAAPHIYQNSFVQV VLNSLIKKSK SSMFQTRSLK ELLWGYKDPF LSLVPYPIST TVGVFYPYND TVDGVYKVFNGKDNISKVAI IESYKGKRNL SYWPSYCDMI NGTDAASFPP FVEKSRTLRF FSSDICRSIY AVFGSEIDLKGIPVYRFVLP ANAFASPLQN PDNHCFCTEK VISNNCTSYG VLDIGKCKEG KPVYISLPHF LHASPDVSEPIEGLHPNEDE HRTYLDVEPI TGFTLQFAKR LQVNILVKPA RKIEALKNLK RPYIVPILWL NETGTIGDEKAEMFKTQVTG KIKHHHHHH. |
Purity | Greaterthan 95.0% as determined by SDS-PAGE. |
Endotoxin | <1.0 EU per μg by the LAL method. |
Formulation | CD36 protein solution (1mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol. |
Stability | Recombinant protein is stable for 12 months at -70°C |
Usage | For Research Use Only |
Storage | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |