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| tag | GST |
| host species | Human |
| accession | NM_006676 |
| synonym | LSFR3A, HVDU2, VDU2, KIAA1003 |
| background | USP20 (ubiquitin carboxyl-terminal hydrolase 20) is a cysteine protease deubiquitinating enzyme belonging to the ubiquitin-specific protease (USP) family and deubiquitinates several proteins such as thyronine deiodinase type 2 (D2), Hypoxia-inducible factor 1α (HIF1α), and β2 adrenergic receptor. It is involved in ADRB2 recycling and resensitization, regulating thyroid hormone regulation and stabilizing and enhancing HIF1A (1). USP20 was also identified to be a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex, as it is involved in the ubiquitination and degradation of HIF1α subunits (2). |
| description | Recombinant human USP20 (120-end) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods. This protein is purified with our unique purification methods. The USP20 gene accession number is NM_006676. |
| source | Sf9 insect cells |
| AA sequence | 120a.a.-end |
| molecular weight | 135 kDa |
| purity | For specific purity information on a given lot, see related COA. |
| endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| bioactivity | Active |
| formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| stability | The recombinant protein is stable for up to 12 months at -70℃ |
| usage | For Research Use Only |
| storage | Recombinant Human USP20 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Cat No. | Product Name | Source | Detail | Inquiry |
| BLA-9545P | Recombinant Human USP20 Protein | Baculovirus infected Sf9 cells |  |
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