Recombinant Human UBA7(UBE1L) Protein
Beta LifeScience
SKU/CAT #: BL-0112SG
Recombinant Human UBA7(UBE1L) Protein
Beta LifeScience
SKU/CAT #: BL-0112SG
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | GST |
Host Species | Human |
Accession | NM_003335 |
Synonym | D8; UBE2; UBA1B; UBA7; UBE1L |
Background | UBA7 or ubiquitin-like modifier activating enzyme 7 is a member of the E1 ubiquitin-activating enzyme family which is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. UBA7 is expressed in a variety of tissues, including normal lung, but highly expressed in a large series of lung cancer cell lines (1). UBA7 may represent a second, autosomal member of the ubiquitin-activating gene family, which play a role in the ubiquitin conjugation pathway, which is of central importance in all eukaryotes (2). |
Description | Recombinant full-length human UBA7 (UBE1L) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods. |
Source | Sf9 insect cells |
AA Sequence | Full Length |
Molecular Weight | ~138 kDa |
Purity | For specific purity information on a given lot, see related COA. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Active |
Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
Stability | The recombinant protein is stable for up to 12 months at -70°C |
Usage | For Research Use Only |
Storage | Recombinant Human UBA7(UBE1L) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |