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Recombinant Human TFG-MET (Tex5Mex15) Protein

Cat No.: BL-0005SG
Description Related products
tag GST
host species Human
accession NM_001195478NM_000245
synonym TFG: HMSNP; SPG57; TF6MET: HGFR, RCCP2
background MET is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 50 kDa (alpha) and 145 kDa (beta). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue (1). Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers and has been shown to be involved in tumor cell migration and invasion (2). The fusion protein of TFG-MET has been found in the spindle cell sarcoma (3).
description Recombinant human TFG (1-193a.a., exons1-5)-MET (1010a.a.-end, exons15-21) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
source Sf9 insect cells
AA sequence 1010a.a.-end, exons15-21
molecular weight 102 kDa
purity For specific purity information on a given lot, see related COA.
endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
bioactivity Active
formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
stability The recombinant protein is stable for up to 12 months at -70℃
usage For Research Use Only
storage Recombinant Human TFG-MET (Tex5Mex15) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Cat No. Product Name Source Detail Inquiry
BL-0010SG Recombinant Human TFG-ALK (Tex4Aex20) Protein Sf9 insect cells
BL-0253SG Recombinant Human TFG-ALK (Tex5Aex20) Protein Sf9 insect cells
BL-0424SG Recombinant Human TFG-TRKA (TRK-T3) Protein Sf9 insect cells
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