Recombinant Human PTH (7-34) Protein
Beta LifeScience
SKU/CAT #: BL-2544PS
Recombinant Human PTH (7-34) Protein
Beta LifeScience
SKU/CAT #: BL-2544PS
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | N/A |
Host Species | Human |
Synonym | PTH/PTHrP receptor antagonist, PTHrP analog, PTHR, MGC138426, MGC138452. |
Background | Polypeptide 60 secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low. Its action is opposed by calcitonin. PTH (7-34), which is a PTH/PTHrP receptor antagonist, can stimulate hair growth and epidermal proliferation in mice. |
Description | Parathyroid Hormone Human Recombinant expressed in E.Coli is a single, non-glycosylated, polypeptide chain containing 28a.a. and having a molecular weight of 3380 Dalton. The PTH is purified by unique purification methods. |
Source | E.coli |
AA Sequence | LMHNLGKHLN SMERVEWLRK KLQDVHNF. |
Purity | >97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
Endotoxin | <1.0 EU per μg by the LAL method. |
Bioactivity | The activity calculated by UMR106 cell/cAMP method corresponding to a specific activity of 10,000 Units/mg. |
Formulation | The protein (1 mg/ml) was lyophilized after extensive dialyses against 20mM PBS pH-7.0 and 150mM NaCl. |
Stability | Recombinant protein is stable for 12 months at -70°C |
Usage | For Research Use Only |
Storage | Lyophilized Parathyrin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PTH should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |