Recombinant Human PD-L2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3757
Recombinant Human PD-L2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3757
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Human |
Accession | NP_079515.2 |
Synonym | PD-L2 Programmed Cell Death 1 Ligand 2; PD-1 Ligand 2; PD-L2; PDCD1 Ligand 2; Programmed Death Ligand 2; Butyrophilin B7-DC; B7-DC; CD273; PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2 |
Background | Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
Description | A DNA sequence encoding the extracellular domain (Met 1-Pro 219) of human PD-L2 (NP_079515.2) was produced with a C-terminal His tag. |
Source | HEK293 |
Predicted N Terminal | Leu 20 |
AA Sequence | Met 1-Pro 219 |
Molecular Weight | The recombinant human PD-L2 consists of 211 amino acids and predicts a molecular mass of 24 kDa. As a result of glycosylation, the apparent molecular mass of rh PD-L2 is approximately 40-45 kDa in SDS-PAGE under reducing conditions. |
Purity | Greater than 98% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Measured by its binding ability in a functional ELISA. Immobilized recombinant human PD-L2 at 1 ug/ml (100 ul/well) can bind recombinant human PD1 with a linear range of 7.8-1000 ng/ml. |
Formulation | Lyophilized from sterile PBS, pH 7.4 |
Stability | Recombinnat Proteins are stable for up to 1 year from date of receipt at -70°C |
Usage | For Research Use Only |