Recombinant Human PD-L2 Protein (His Tag), Biotinylated
Beta LifeScience
SKU/CAT #: BLPSN-3758
Recombinant Human PD-L2 Protein (His Tag), Biotinylated
Beta LifeScience
SKU/CAT #: BLPSN-3758
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Human |
Accession | NP_079515.2 |
Synonym | PD-L2 Programmed Cell Death 1 Ligand 2; PD-1 Ligand 2; PD-L2; PDCD1 Ligand 2; Programmed Death Ligand 2; Butyrophilin B7-DC; B7-DC; CD273; PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2 |
Background | Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
Description | A DNA sequence encoding the extracellular domain (Met1-Pro219) of human PD-L2 (NP_079515.2) was produced with a C-terminal His tag. The purified protein was biotinylated in vitro. |
Source | HEK293 |
Predicted N Terminal | Leu 20 |
AA Sequence | NP_079515.2 |
Molecular Weight | The recombinant human PD-L2 consists of 211 amino acids and predicts a molecular mass of 24 kDa. |
Purity | Greater than 95% as determined by SDS-PAGE. |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
Bioactivity | Measured by its ability to bind human PD1-Fch in functional ELISA. |
Formulation | Lyophilized from sterile PBS,pH7.4. |
Stability | Recombinnat Proteins are stable for up to 1 year from date of receipt at -70°C |
Usage | For Research Use Only |