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Recombinant Human MOG Protein (His Tag)

Cat No.: BL-0002NP
Description Related products
tag His
host species Human
accession Q16653
synonym MOG Myelin-Oligodendrocyte Glycoprotein; MOG
background Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.
description Recombinant Human Myelin Oligodendrocyte Glycoprotein is expressed by our E.coli expression system and the target gene encoding Gly30-Gly154 is expressed with a His tag at the C-terminus.
source E.coli
AA sequence Gly30-Gly154
purity >95% as determined by reducing SDS-PAGE.
endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
formulation Recombinant Human MOG Protein was lyophilized from a 0.2 μm filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5.
reconstitution Dissolve the lyophilized protein in distilled water.
usage For Research Use Only
storage Human MOG protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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