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| tag | GST |
| host species | Human |
| accession | NM_000245 |
| synonym | HGFR, RCCP2 |
| background | MET is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 50 kDa (alpha) and 145 kDa (beta). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue (1). Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers and has been shown to be involved in tumor cell migration and invasion (2). |
| description | Recombinant human MET (D1228G) (956-end) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods. |
| source | Sf9 insect cells |
| AA sequence | 956a.a.-end |
| molecular weight | 81 kDa |
| purity | For specific purity information on a given lot, see related COA. |
| endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| bioactivity | Active |
| formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| stability | The recombinant protein is stable for up to 12 months at -70℃ |
| usage | For Research Use Only |
| storage | Recombinant Human MET (D1228G) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
