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Recombinant Human IRAK4 (catalytic domain) Protein

Cat No.: BL-0006SG
Description Related products
tag GST
host species Human
accession BC013316
synonym IPD1, REN64, NY-REN-64
background Interleukin-1 receptor-associated kinase 4 (IRAK4) is an important mediator in the signal transduction of Toll-like receptor (TLR) and IL1R family members (1). IRAK4 is involved in the Toll-like receptor signaling pathway leading to Apoptosis. IRAK4 has molecular functions like protein binding, ATP binding, kinase activity and magnesium ion binding. Toll/IL-1 receptor family members like IRAK4 are central components of host defense mechanisms in a variety of species (2). One well conserved element in their signal transduction is the Ser/Thr kinase activity which couple early signaling events in a receptor complex at the plasma membrane to larger signalosomes in the cytosol
description Recombinant human IRAK4 (104 a.a.-end) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
source Sf9 insect cells
AA sequence 104 a.a.-end
molecular weight 68 kDa
purity For specific purity information on a given lot, see related COA.
endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
bioactivity Active
formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
stability The recombinant protein is stable for up to 12 months at -70℃
usage For Research Use Only
storage Recombinant Human IRAK4 (catalytic domain) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Cat No. Product Name Source Detail Inquiry
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