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Recombinant Human EphA4 Protein (Fc Tag)

Cat No.: BL-0010NP
Description Related products
tag Fc
host species Human
accession P54764
synonym EphA4 Ephrin type-A receptor 4;HEK8; SEK; TYRO1;EPHA4;Tyrosine-protein kinase receptor SEK;Tyrosine-protein kinase TYRO1;EK8;hEK8;EPH-like kinase 8
background Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
description Recombinant Human Ephrin type A receptor 4 is expressed by our Mammalian expression system and the target gene encoding Val20-Thr547 is expressed with a Fc tag at the C-terminus.
source Human Cells
AA sequence Val20-Thr547
purity >95% as determined by reducing SDS-PAGE.
endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
bioactivity Measured by its ability to binding recombinant human Ephrin-A5 used funtional ELISA. The ED50 for this binding effect is 66.8nM when EphA4 2ug/ml in a solid phases. 
formulation Recombinant Human EphA4 Protein was lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
reconstitution Dissolve the lyophilized protein in distilled water.
usage For Research Use Only
storage Human EphA4 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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