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| tag | GST |
| host species | Human |
| accession | NM_001365405 |
| synonym | iCE; CE-2; PCE-2; CES2A1 |
| background | Carboxylesterase 2 (CES2) is a member of the carboxylesterase family, which catalyzes the hydrolysis transesterification of various xenobiotic and endogenous substrates with ester, thioester, or amide bonds to detoxify the xenobiotics and activate the prodrugs (1). CES2 is mainly expression in intestine to hydrolyze substrates with a large alcohol group and small acyl group such as aspirin, the anticancer prodrug irinotecan (CPT-11), and flutamide (2). In addition, CES2 is also involved in obesity and fatty liver disease, which is related in lipid metabolism (2). |
| description | Recombinant full length human CES2 was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods. |
| source | Sf9 insect cells |
| AA sequence | Full Length |
| molecular weight | 90 kDa |
| purity | For specific purity information on a given lot, see related COA. |
| endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| bioactivity | Active |
| formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| stability | The recombinant protein is stable for up to 12 months at -70℃ |
| usage | For Research Use Only |
| storage | Recombinant Human CES2 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Cat No. | Product Name | Source | Detail | Inquiry |
| BLPSN-1223 | Recombinant Human CES2 Protein (His Tag) | HEK293 |  |
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| BLPSN-1224 | Recombinant Mouse CES2 Protein (His Tag) | HEK293 | |
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