USA  Tel: 1-201-888-7983
Email: info@betalifesci.com

Recombinant Human CD1E Protein

Cat No.: BL-0004PS
CD1E Human Recombinant
Description Related products
tag His
host species Human
synonym CD1A, R2, T-cell surface glycoprotein CD1e, membrane-associated, R2G1, sCD1e.
background CD1E belongs to the CD1family of transmembrane glycoproteins which are structurally associated to the mainMHC (histocompatibility complex) proteins and form heterodimers withbeta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipidand glycolipid antigens of self or microbial origin to T cells. The humangenome is comprised of 5 CD1 family genes organized in a cluster on chromosome1. The CD1 family members are belief to differ in their cellular localizationand specificity for particular lipid ligands. CD1E localizes within Golgicompartments, endosomes, and lysosomes, and is cleaved into a steady solubleform. The soluble form is necessary for the intracellular processing of someglycolipids into a form that can be presented by other CD1 family members.
description CD1E Human Recombinant expressed in E.Coli is a single,non-glycosylated polypeptide chain containing 297a.a. (32-305 a.a) andhaving a molecular weight of 33.1kDa.CD1E is fused to a 23a.a. His-tag at N-terminus and purified by unique purification methods.
source E.coli
AA sequence MGSSHHHHHH SSGLVPRGSH MGSEEQLSFR MLQTSSFANH SWAHSEGSGW LGDLQTHGWD TVLGTIRFLKPWSHGNFSKQ ELKNLQSLFQ LYFHSFIQIV QASAGQFQLE YPFEIQILAG CRMNAPQIFL NMAYQGSDFLSFQGISWEPS PGAGIRAQNI CKVLNRYLDI KEILQSLLGH TCPRFLAGLM EAGESELKRK VKPEAWLSCGPSPGPGRLQL VCHVSGFYPK PVWVMWMRGE QEQRGTQRGD VLPNADETWY LRATLDVAAG EAAGLSCRVKHSSLGGHDLI IHWGGYS.
purity >85.0% as determined by SDS-PAGE.
endotoxin <1.0 EU per μg by the LAL method.
formulation CD1E protein solution (1mg/ml) contains 20mM Tris-HCl buffer(pH 8.0), 10% glycerol and 0.4M Urea.
stability Recombinant protein is stable for 12 months at -70℃
usage For Research Use Only
storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Cat No. Product Name Source Detail Inquiry
BLPSN-0761 Recombinant Cynomolgus CD1E & B2M Heterodimer Protein (His Tag) HEK293
BLA-10896P Recombinant Human CD1E Protein (denatured) E.coli
Online Inquiry
For quote, please fill in the online form or send email to info@betalifesci.com.
$50 Coupon