Recombinant Human ARG1 Protein (His & MYC Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0253
Recombinant Human ARG1 Protein (His & MYC Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0253
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His&MYC |
Host Species | Human |
Accession | NP_000036.2 |
Synonym | ARG1 |
Background | Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of L-arginine to L-ornithine and the formation of polyamines and L-proline, which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals, Arginase 1 (ARG1) also known as Arginase, liver, which functions in the urea cycle, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body, with most abundance in the kidney and prostate. It may be found at lower levels in macrophages, lactating mammary glands, and brain. |
Description | A DNA sequence encoding the human ARG1 (NP_000036.2) (Met1-Lys322) was expressed with a His tag at the N-terminus and a myc tag at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | His |
AA Sequence | Met1-Lys322 |
Molecular Weight | The recombinant human ARG1 consists of 338 a.a. and predicts a molecular mass of 36.7 kDa. |
Purity | >95% as determined by SDS-PAGE. |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 20 % glycerol, pH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |