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Recombinant Cynomolgus CD40 Protein (Fc Tag)

Cat No.: BL-0215NP
Description Related products
tag Fc
host species Cynomolgus
accession G7PG38
synonym CD40 Tumor Necrosis Factor Receptor Superfamily member 5; B-Cell Surface Antigen CD40; Bp50; CD40L Receptor; CDw40; CD40; TNFRSF5
background CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction.
description Recombinant Cynomolgus CD40 molecule is expressed by our Mammalian expression system and the target gene encoding Glu21-Arg193 is expressed with a Fc tag at the C-terminus.
source Human Cells
AA sequence Glu21-Arg193
purity >90% as determined by reducing SDS-PAGE.
endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
formulation Recombinant Cynomolgus CD40 Protein was lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH7.5.
reconstitution Dissolve the lyophilized protein in distilled water.
usage For Research Use Only
storage Cynomolgus CD40 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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