tag |
His |
host species |
2019-nCoV |
accession |
YP_009725306.1 |
synonym |
SARS-CoV 2 nsp10; SARS-CoV 2 Growth factor-like peptide; SARS-CoV 2 GFL |
background |
Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing. |
description |
Recombinant 2019-nCoV NSP10 is produced by our E.coli expression system and the target gene encoding Ala1-Gln139 is expressed with a 6His tag at the N-terminus. |
source |
E.coli |
AA sequence |
Ala1-Gln139 |
molecular weight |
17.9kDa. AP Mol Mass: 18kDa, reducing conditions. |
purity |
>80% as determined by reducing SDS-PAGE. |
formulation |
Recombinant 2019-nCoV NSP10 was Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4. |
Sensitivity |
For Research Use Only |
Detection Limit |
Store at < -20°C, stable for 6 months after receipt. Please Avoid repeated freeze-thaw cycles. |