Recombinant Rhesus FGFR4 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2084
Recombinant Rhesus FGFR4 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2084
Catalog No.: BLPSN-2084
Product Overview
| Tag | Fc |
| Host Species | Rhesus |
| Accession | XP_001087243.1 |
| Synonym | FGFR4, CD334, JTK2, TKF, fibroblast growth factor receptor 4 |
| Background | Fibroblast growth factor receptor 4 is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as CD334 (cluster of differentiation 334).FGFR4 (Fibroblast Growth Factor Receptor 4) is a Protein Coding gene. Diseases associated with FGFR4 include Prostate Cancer and Rhabdomyosarcoma. Among its related pathways are PI3K/AKT activation and RET signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR3. |
| Description | A DNA sequence encoding the rhesus FGFR4 (XP_001087243.1) was expressed with the Fc region of mouse IgG1 at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Leu 22 |
| AA Sequence | Met1-Asp369 |
| Molecular Weight | The recombinant rhesus FGFR4 comprises 589 amino acids and has a calculated molecular mass of 65.6 KDa. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Measured by its binding ability in a functional ELISA.1. Immobilized human FGF18-His at 10 ug/ml (100 ul/well) can bind cynoFGFR4-Fc with a linear range of 0.25-2.0 ug/ml.2. Immobilized human FGF basic at 10 ug/ml (100 ul/well) can bind cynoFGFR4-Fc with a linear range of 0.03-0.25 ug/ml. |
| Formulation | Recombinant Rhesus FGFR4 Protein (Fc Tag) was lyophilized from sterile PBS, pH 7.4 |
| Stability | Recombinant Rhesus FGFR4 protein is stable up to 1 year at -70°C |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
