Recombinant Rhesus CLEC5A Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1319
Recombinant Rhesus CLEC5A Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1319
Catalog No.: BLPSN-1319
Product Overview
| Tag | His |
| Host Species | Rhesus |
| Accession | XP_001085243.1 |
| Background | CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release. |
| Description | A DNA sequence encoding the rhesus CLEC5A (XP_001085243.1) (Pro28-Arg188) was expressed with a His tag at the N-terminus. |
| Source | HEK293 |
| Predicted N Terminal | His |
| AA Sequence | Pro28-Arg188 |
| Molecular Weight | The recombinant rhesus CLEC5A comprises 181 a.a. and has a calculated molecular mass of 21 KDa.. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
