Recombinant Rhesus CLEC5A Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1319
Recombinant Rhesus CLEC5A Protein (His Tag)

Recombinant Rhesus CLEC5A Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1319
Catalog No.: BLPSN-1319

Product Overview

Tag His
Host Species Rhesus
Accession XP_001085243.1
Background CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
Description A DNA sequence encoding the rhesus CLEC5A (XP_001085243.1) (Pro28-Arg188) was expressed with a His tag at the N-terminus.
Source HEK293
Predicted N Terminal His
AA Sequence Pro28-Arg188
Molecular Weight The recombinant rhesus CLEC5A comprises 181 a.a. and has a calculated molecular mass of 21 KDa..
Purity >95% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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