Recombinant Rat UNC5B Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4740
Recombinant Rat UNC5B Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4740
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | Fc |
Host Species | Rat |
Accession | NP_071543.1 |
Background | The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. In addition, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. |
Description | A DNA sequence encoding the rat UNC5B (NP_071543.1) (Met1-Asp373) was expressed with the Fc region of human IgG1 at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Gly 27 |
AA Sequence | Met1-Asp373 |
Molecular Weight | The recombinant rat UNC5B/Fc is a disulfide-linked homodimer. The reduced monomer comprises 588 a.a. and has a predicted molecular mass of 65.7 kDa. The apparent molecular mass of the protein is approximately 72-90 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Purity | >85% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |