Recombinant Rat PFN1 Protein

Beta LifeScience SKU/CAT #: BL-4435PS
Recombinant Rat PFN1 Protein

Recombinant Rat PFN1 Protein

Beta LifeScience SKU/CAT #: BL-4435PS
Catalog No.: BL-4435PS

Product Overview

Tag N/A
Host Species Rat
Synonym Profilin-1, Profilin I.
Background Profilin-1 also known as Pfn1 is a ubiquitous actin monomer-bindingprotein which is a member of the profilin family. Pfn1 significantly enhancesskin wound healing in-vitro as well as in-vivo which is mediated by purinergicreceptors. Furthermore, Pfn1 is also active in endothelial cell migration andvessel sprouting. Pfn1 is considered to regulate actin polymerization inresponse to extracellular signals.
Description PFN1 Rat Recombinant expressed in E.Coli is a single,non-glycosylated polypeptide chain containing 164a.a. (1-140 a.a) andhaving a molecular weight of 17.5kDa.PFN1 is fused to a 24a.a. His-tag at N-terminusand purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSHMAGWNA YIDSLMADGT CQDAAIVGYK DSPSVWAAVP GKTFVSITPAEVGVLVGKDR SSFFVNGLTL GGQKCSVIRD SLLQDGEFTM DLRTKSTGGA PTFNVTVTMT AKTLVLLMGKEGVHGGLINK KCYEMASHLR RSQY.
Purity >95.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation PFN1 protein solution (1mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol 1mM DTT.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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