Recombinant Mouse TMED1 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4560
Recombinant Mouse TMED1 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4560
Catalog No.: BLPSN-4560
Product Overview
| Tag | Fc |
| Host Species | Mouse |
| Accession | NP_034874.2 |
| Synonym | Il1rl1l, Ly84l, St2l |
| Background | TMED1 belongs to the EMP24/GP25L family. It contains 1 GOLD domain and is widely expressed. TMED1 binds to its receptor IL1RL1 and results in the activation of DNA binding by nuclear factor NF-kappa-B or transcription from the IL8 promoter and most likely requires other proteins to elicit these activities. Dendritic cells from Peyer's patches (but not from spleen) express TMED1 in response to treatment with LPS. TMED1 may play a role in vesicular protein trafficking, mainly in the early secretory pathway. It may act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. |
| Description | A DNA sequence encoding the mouse TMED1 (NP_034874.2) (Met1-Asn194) was expressed with the Fc region of human IgG1 at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Gly 25 |
| AA Sequence | Met1-Asn194 |
| Molecular Weight | The recombinant mouse TMED1 consists of 408 a.a. and predicts a molecular mass of 46 kDa. |
| Purity | >85% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
