Recombinant Mouse PSGL-1 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0074NP
Recombinant Mouse PSGL-1 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0074NP
Catalog No.: BL-0074NP
Product Overview
| Tag | Fc |
| Host Species | Mouse |
| Accession | Q62170 |
| Synonym | PSGL-1 CLA; CD162; PSGL1; PSGL-1 |
| Background | P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin. |
| Description | Recombinant Mouse P-selectin glycoprotein ligand 1 is expressed by our Mammalian expression system and the target gene encoding Gln42-Cys307 is expressed with a Fc tag at the C-terminus. |
| Source | Human Cells |
| AA Sequence | Gln42-Cys307 |
| Purity | >95% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Recombinant Mouse PSGL-1 Protein was lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Reconstitution | Dissolve the lyophilized protein in distilled water. |
| Usage | For Research Use Only |
| Storage | Mouse PSGL-1 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
