Recombinant Mouse PODXL Protein

Beta LifeScience SKU/CAT #: BL-4111PS
Recombinant Mouse PODXL Protein

Recombinant Mouse PODXL Protein

Beta LifeScience SKU/CAT #: BL-4111PS
Catalog No.: BL-4111PS

Product Overview

Tag His
Host Species Mouse
Synonym Podocalyxin,Podocalyxin-like protein 1, PC, PCLP-1.
Background Podocalyxin (PODXL) is a greatly glycosylated transmembrane sialoprotein in the CD34 and endoglycan family. The PODXL protein is involved in the regulation of both adhesion and cell morphology and cancer progression. PODXL functions as an anti-adhesive molecule, which retains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Moreover, PODXL serves as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner.
Description PODXL Mouse Recombinant expressed in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 391a.a. (22-404a.a.) and having a molecular weight of 41.0kDa (Molecular size on SDS-PAGE will appear at approximately 70-100kDa).PODXL is expressed with an 8a.a. His tag at C-Terminus and purified by unique purification methods.
Source Sf9
AA Sequence HNGNETSTSA IKSSTVQSHQ SATTSTEVTT GHPVASTLAS TQPSNPTPFTTSTQSPSMPT STPNPTSNQS GGNLTSSVSE VDKTKTSSPS STAFTSSSGQ TASSGGKSGD SFTTAPTTTLGLINVSSQPT DLNTTSKLLS TPTTDNTTSP QQPVDSSPST ASHPVGQHTP AAVPSSSGSTPSTDNSTLTW KPTTHKPLGT SEATQPLTSQ TPGITTLPVS TLQQSMASTVGTTTEEFTHL ISNGTPVAPP GPSTPSPIWA FGNYQLNCEP PIRPDEELLI LNLTRASLCE RSPLDEKEKLVELLCHSVKA SFKPAEDLCT LHVAPILDNQ AVAVKRIIIE TKLSPKAVYE LLKDRWDDLTEAGVSDMKLG KEGPPEVNED RFSLEHHHHH H.
Purity Greaterthan 95% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation PODXL protein solution (0.5mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
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