Recombinant Mouse PODXL Protein
Beta LifeScience
SKU/CAT #: BL-4111PS
Recombinant Mouse PODXL Protein
Beta LifeScience
SKU/CAT #: BL-4111PS
Collections: Other recombinant proteins, Recombinant proteins
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Product Overview
Tag | His |
Host Species | Mouse |
Synonym | Podocalyxin,Podocalyxin-like protein 1, PC, PCLP-1. |
Background | Podocalyxin (PODXL) is a greatly glycosylated transmembrane sialoprotein in the CD34 and endoglycan family. The PODXL protein is involved in the regulation of both adhesion and cell morphology and cancer progression. PODXL functions as an anti-adhesive molecule, which retains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Moreover, PODXL serves as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. |
Description | PODXL Mouse Recombinant expressed in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 391a.a. (22-404a.a.) and having a molecular weight of 41.0kDa (Molecular size on SDS-PAGE will appear at approximately 70-100kDa).PODXL is expressed with an 8a.a. His tag at C-Terminus and purified by unique purification methods. |
Source | Sf9 |
AA Sequence | HNGNETSTSA IKSSTVQSHQ SATTSTEVTT GHPVASTLAS TQPSNPTPFTTSTQSPSMPT STPNPTSNQS GGNLTSSVSE VDKTKTSSPS STAFTSSSGQ TASSGGKSGD SFTTAPTTTLGLINVSSQPT DLNTTSKLLS TPTTDNTTSP QQPVDSSPST ASHPVGQHTP AAVPSSSGSTPSTDNSTLTW KPTTHKPLGT SEATQPLTSQ TPGITTLPVS TLQQSMASTVGTTTEEFTHL ISNGTPVAPP GPSTPSPIWA FGNYQLNCEP PIRPDEELLI LNLTRASLCE RSPLDEKEKLVELLCHSVKA SFKPAEDLCT LHVAPILDNQ AVAVKRIIIE TKLSPKAVYE LLKDRWDDLTEAGVSDMKLG KEGPPEVNED RFSLEHHHHH H. |
Purity | Greaterthan 95% as determined by SDS-PAGE. |
Endotoxin | <1.0 EU per μg by the LAL method. |
Formulation | PODXL protein solution (0.5mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol. |
Stability | Recombinant protein is stable for 12 months at -70°C |
Usage | For Research Use Only |
Storage | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |