Recombinant Mouse Frizzled 2 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2144
Recombinant Mouse Frizzled 2 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2144
Catalog No.: BLPSN-2144
Product Overview
| Tag | Fc |
| Host Species | Mouse |
| Accession | NP_065256.1 |
| Synonym | AL033370, AW456835, Fz10, Fzd10, Mfz10, Mfz10a |
| Background | FZD2 may be a tumor suppressor gene in salivary adenoid cystic carcinomas (SACCs) that inhibits cell growth and migration. OMOD2 is a rare skeletal dysplasia and characterized by facial dysmorphism and shortness of the upper extremities and first metacarpal bones, and heterozygous FZD2 mutations may be disease-causing for OMOD2. heterozygous de novo mutation (G434V) in the frizzled class receptor 2 (FZD2) gene in a patient with distinct facial features including hypertelorism, bilateral cleft lip/palate, short nose with a broad nasal bridge, microretrognathia, and bilateral shortness of the upper limbs, |
| Description | A DNA sequence encoding the mouse Fzd2 (NP_065256.1) (Gln29-Leu168) was expressed with the Fc region of human IgG1 at the N-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Glu |
| AA Sequence | Gln29-Leu168 |
| Molecular Weight | The recombinant mouse Fzd2 consists of 400 a.a. and predicts a molecular mass of 44.2 kDa. |
| Purity | >90% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
