Recombinant Mouse Fractalkine / CX3CL1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2138
Recombinant Mouse Fractalkine / CX3CL1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2138
Product Overview
| Tag | His |
| Host Species | Mouse |
| Accession | NP_033168.2 |
| Synonym | AB030188, ABCD-3, AI848747, CX3C, Cxc3, D8Bwg0439e, Scyd1 |
| Background | Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine / CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines. |
| Description | A DNA sequence encoding the mouse Cx3cl1 (NP_033168.2) (Gln25-Lys105) was expressed with a His tag at the C-terminus. |
| Source | Yeast |
| Predicted N Terminal | Gln 25 |
| AA Sequence | Gln25-Lys105 |
| Molecular Weight | The recombinant mouse Cx3cl1 consists of 91 a.a. and predicts a molecular mass of 10.7 kDa. |
| Purity | >95% as determined by SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, PH 7.40.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
