Recombinant Mouse FCRL1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-2017
Recombinant Mouse FCRL1 Protein (His Tag)

Recombinant Mouse FCRL1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-2017
Catalog No.: BLPSN-2017

Product Overview

Tag His
Host Species Mouse
Accession Q8R4Y0
Synonym A230020G22Rik, Bxmas1, Bxmh1, Bxmh1b, Fcrh1, Fcrh1l, Fcrh1s, Ifgp1
Background Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which contains threeIg-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.
Description A DNA sequence encoding the mouse FCRL1 (Q8R4Y0-2) (Met1-Thr204) was expressed with a C-terminal His tag.
Source HEK293
Predicted N Terminal Ala 17
AA Sequence Met1-Thr204
Molecular Weight The recombinant mouse FCRL1 comprises 199 a.a. and has a predicted molecular mass of 21.6 kDa. The apparent molecular mass of the protein is approximately 42-47 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Purity >95% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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