Recombinant Mouse DKK3 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1622
Recombinant Mouse DKK3 Protein (His Tag)

Recombinant Mouse DKK3 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1622
Catalog No.: BLPSN-1622

Product Overview

Tag His
Host Species Mouse
Accession NP_056629.1
Synonym AW061014, C87148
Background DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.
Description A DNA sequence encoding the extracellular domain (Met 1-Ile 349) of mouse DKK3 (NP_056629.1) precursor was expressed with a C-terminal His tag.
Source HEK293
Predicted N Terminal Pro 23
AA Sequence Met 1-Ile 349
Molecular Weight The secreted recombinant mouse DKK3 consists of 338 a.a. and has a calculated molecular mass of 38 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 65 kDa protein in SDS-PAGE under reducing conditions.
Purity >97% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recently viewed