Recombinant Mouse Cathepsin E Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-0602
Recombinant Mouse Cathepsin E Protein (His Tag)

Recombinant Mouse Cathepsin E Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-0602
Catalog No.: BLPSN-0602

Product Overview

Tag His
Host Species Mouse
Accession NP_031825.2
Synonym A430072O03Rik, C920004C08Rik, CatE, CE
Background Cathepsin E Protein (CTSE Protein) is a member of the peptidase C1 family that is a gastric aspartic protease that functions as a disulfide-linked homodimer. Cathepsin E Protein (CTSE Protein) is predominantly present in the cells of immune system and is frequently implicated in antigen processing via the MHC class-…¡ pathway which however does not appear to be involved in the digestion of dietary protein. The protein has a specificity similar to that of pepsin and pepsin. Cathepsin E Protein (CTSE Protein) is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach and also been found in more than half of the gastric cancers. It appears, therefore, to be an oncofetal antigen.
Description A DNA sequence encoding the extracellular domain of mouse CTSE (NP_031825.2) (Met 1-Pro 397) was expressed, with a His tag at the C-terminus.
Source HEK293
Predicted N Terminal Gln 19
AA Sequence Met 1-Pro 397
Molecular Weight The secreted recombinant mouse CTSE (pro form) consists of 390 a.a. and has a predicted molecular mass of 42.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCTSE is approximately 45-48 kDa due to glycosylation.
Purity >97% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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