Recombinant Mouse C-Reactive Protein Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1416
Recombinant Mouse C-Reactive Protein Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1416
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Mouse |
Accession | NP_031794.3 |
Synonym | AI255847 |
Background | C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monitor many human diseases. However, CRP is likely to have important host defence, scavenging and metabolic functions through its capacity for calcium-dependent binding to exogenous and autologous molecules containing phosphocholine (PC) and then activating the classical complement pathway. CRP may also have pathogenic effects and the recent discovery of a prognostic association between increased CRP production and coronary atherothrombotic events is of particular interest. |
Description | A DNA sequence encoding the mouse CRP (NP_031794.3) (Met 1-Ser 225) was expressed, with a C-terminal His tag. |
Source | HEK293 |
Predicted N Terminal | Glu 21 |
AA Sequence | Met 1-Ser 225 |
Molecular Weight | The secreted recombinant mouse CRP consists of 216 a.a. and has a calculated molecular mass of 24.4 kDa. As a result of glycosylation, the apparent molecular mass of rmCRP is approximately 30 kDa in SDS-PAGE under reducing conditions. |
Purity | >94% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |