Name: Recombinant Mouse Bone Alkaline Phosphatase Protein (Fc Tag)
Brand: Beta LifeScience
SKU: BLPSN-0445
Availability: InStock

Recombinant Mouse Bone Alkaline Phosphatase Protein (Fc Tag)

Collections: Other recombinant proteins, Recombinant proteins

Product Overview

Tag	Fc
Host Species	Mouse
Accession	BAH03518.1
Synonym	Akp-2, Akp2, APTNAP, TNAP, TNSALP
Background	Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is called dephosphorylation. As the name suggests, alkaline phosphatases are most effective in an alkaline environment. It is sometimes used synonymously as basic phosphatase. Alkaline phosphatases (APs) are ubiquitous in many species, from bacteria to human. Four genes encode AP isoenzymes in humans and rodents. Three AP genes are expressed in a tissue-specific manner (i.e., placental, embryonic, and intestinal AP isoenzymes). Expression of the fourth AP gene is nonspecific to a single tissue and is especially abundant in bone, liver, and kidney. This isoenzyme is also called tissue-nonspecific alkaline phosphatase (TNAP). The enzyme tissue non-specific alkaline phosphatase (TNAP) belongs to the ectophosphatase family. TNAP is present in large amounts in bone in which it plays a role in mineralization.
Description	A DNA sequence encoding the mouse Alpl (BAH03518.1) (Met1-Ser502) was expressed with the Fc region of human IgG1 at the C-terminus.
Source	HEK293
Predicted N Terminal	Phe 18
AA Sequence	Met1-Ser502
Molecular Weight	The recombinant mouse Alpl consists 723 a.a. and predicts a molecular mass of 80.3 kDa.
Purity	>90% as determined by SDS-PAGE.
Endotoxin	< 1.0 EU per μg protein as determined by the LAL method.
Bioactivity	Please contact us for detailed information
Formulation	Lyophilized from sterile PBS, pH 7.4..
Stability	The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage	For Research Use Only
Storage	Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.