Recombinant Mouse APRIL Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0247
Recombinant Mouse APRIL Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0247
Catalog No.: BLPSN-0247
Product Overview
| Tag | Fc |
| Host Species | Mouse |
| Accession | Q9D777 |
| Synonym | 2310026N09Rik, April, Tall2, Trdl1 |
| Background | TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. It is a ligand for TNFRSF17/BCMA. TNFSF13 is lowly expressed in normal tissues, but is elevated in several types of tumors and transformed cell lines. It is mportant for B cell development. TNFSF13 may also play a role in T-independent type II antigen responses and T cell survival, and induce proliferation/survival of non lymphoid cells. It exists as a functional homotrimer. It can bind to two cell surface receptors, BCMA and TACI, which it shares with BAFF to exert downstream T- and B-cell regulatory effects. TNFSF13 also has been demonstrated to bind to proteoglycans on the cell surface. |
| Description | A DNA sequence encoding the mouse TNFSF13 (Q9D777) (Ala96-Leu240) was expressed with the fused Fc region of human IgG1 at the N-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Glu |
| AA Sequence | Ala96-Leu240 |
| Molecular Weight | The recombinant mouse TNFSF13/Fc comprises 405 a.a. and has a predicted molecular mass of 44.8 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
