Recombinant Mouse ADAM9 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0088

Recombinant Mouse ADAM9 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0088
Catalog No.: BLPSN-0088
Product Overview
Tag | His |
Host Species | Mouse |
Accession | Q61072 |
Synonym | AU020942, MDC9, mKIAA0021, Mltng |
Background | ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various human cancers, and plays a role in tumorigenesis in mouse models. ADAM9 cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as EGF, FGFR2iiib, Tie-2, Flk-1, EphB4, CD4, VCAM-1, and VE-cadherin, and could represent a potential therapeutic target in tumors where it is highly expressed. ADAM9 belongs to a family of transmembrane, disintegrin-containing metalloproteinases involved in protein ectodomain shedding and cell-cell and cell-matrix interactions. ADAM-9 adhesive domain plays a role in regulating the motility of cells by interaction with beta1 integrins and modulates MMP synthesis. |
Description | A DNA sequence encoding the mouse ADAM9 (Q61072) extracellular domain (Met 1-Asp 697) was expressed with a C-terminal His tag. |
Source | HEK293 |
Predicted N Terminal | Gly 30 |
AA Sequence | Met 1-Asp 697 |
Molecular Weight | The secreted recombinant mouse ADAM9 consists of 679 a.a. and has a calculated molecular mass of 74.9 kDa. |
Purity | >87% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |