Name: Recombinant Mouse ADAM9 Protein (His Tag)
Brand: Beta LifeScience
SKU: BLPSN-0088
Availability: InStock

Recombinant Mouse ADAM9 Protein (His Tag)

Catalog No.: BLPSN-0088

Product Overview

Tag	His
Host Species	Mouse
Accession	Q61072
Synonym	AU020942, MDC9, mKIAA0021, Mltng
Background	ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various human cancers, and plays a role in tumorigenesis in mouse models. ADAM9 cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as EGF, FGFR2iiib, Tie-2, Flk-1, EphB4, CD4, VCAM-1, and VE-cadherin, and could represent a potential therapeutic target in tumors where it is highly expressed. ADAM9 belongs to a family of transmembrane, disintegrin-containing metalloproteinases involved in protein ectodomain shedding and cell-cell and cell-matrix interactions. ADAM-9 adhesive domain plays a role in regulating the motility of cells by interaction with beta1 integrins and modulates MMP synthesis.
Description	A DNA sequence encoding the mouse ADAM9 (Q61072) extracellular domain (Met 1-Asp 697) was expressed with a C-terminal His tag.
Source	HEK293
Predicted N Terminal	Gly 30
AA Sequence	Met 1-Asp 697
Molecular Weight	The secreted recombinant mouse ADAM9 consists of 679 a.a. and has a calculated molecular mass of 74.9 kDa.
Purity	>87% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity	Please contact us for detailed information
Formulation	Lyophilized from sterile PBS, pH 7.4.
Stability	The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage	For Research Use Only
Storage	Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.