Name: Recombinant Human ZFAND5 Protein
Brand: Beta LifeScience
SKU: BL-4929PS
Availability: InStock

Catalog No.: BL-4929PS

Product Overview

Tag	N/A
Host Species	Human
Synonym	Zinc Finger, AN1-Type Domain 5, Zinc Finger Protein 216, ZNF216,Zinc Finger A20 Domain-Containing Protein 2, Zinc Finger, A20 Domain Containing2, ZA20D2, AN1-Type Zinc Finger Protein 5, ZFAND5A, AN1-type zinc fingerprotein 5, Zinc finger A20 domain-containing protein 2, Zinc finger protein 216.
Background	Zinc Finger, AN1-Type Domain 5, also known as ZFAND5 is implicated inprotein degradation through the ubiquitin-proteasome system. ZFAND5 performs byanchoring ubiquitinated proteins to the proteasome and takes part inubiquitin-mediated protein degradation during muscle atrophy. Furthemore,ZFAND5 plays a role in the regulation of NF-kappa-B activation as well asapoptosis. ZFAND5 inhibits NF-kappa-B activation as well as tumor necrosisfactor (TNF), IL-1 and TLR4-induced NF-kappa-B activation.
Description	ZFAND5 Human Recombinant expressed in E.Coli is a single, non-glycosylatedpolypeptide chain containing 236a.a. (1-213 a.a) and having a molecularmass of 25.5kDa (Molecular size on SDS-PAGE will appear higher).ZFAND5 is fused to a 23a.a. His-tag at N-terminusand purified by unique purification methods.
Source	E.coli
AA Sequence	MGSSHHHHHH SSGLVPRGSH MGSMAQETNQ TPGPMLCSTG CGFYGNPRTN GMCSVCYKEH LQRQQNSGRMSPMGTASGSN SPTSDSASVQ RADTSLNNCE GAAGSTSEKS RNVPVAALPV TQQMTEMSIS REDKITTPKTEVSEPVVTQP SPSVSQPSTS QSEEKAPELP KPKKNRCFMC RKKVGLTGFD CRCGNLFCGL HRYSDKHNCPYDYKAEAAAK IRKENPVVVA EKIQRI.
Purity	>85.0% as determined by SDS-PAGE.
Endotoxin	<1.0 EU per μg by the LAL method.
Formulation	ZFAND5 protein solution (0.5mg/ml) containing 20mM Phosphatebuffer saline (pH 8.0), 30% glycerol and 1mM DTT.
Stability	Recombinant protein is stable for 12 months at -70°C
Usage	For Research Use Only
Storage	Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.