Recombinant Human Vinculin Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-4813
Recombinant Human Vinculin Protein (His Tag)

Recombinant Human Vinculin Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-4813
Catalog No.: BLPSN-4813

Product Overview

Tag His
Host Species Human
Accession P18206
Synonym CMD1W, CMH15, HEL114, MV, MVCL
Background Vinculin (VCL) is a cytoskeletal protein that is closely related to both cell-matrix interactions and cell-cell junctions. VCL is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. This protein has multi-ligand properties and has been found to interact with a number of microfilament associated proteins, such as talin, a-actinin, and paxillin, which reportedly bind to either the head or tail domains of vinculin.
Description A DNA sequence encoding the human VCL (P18206-2) (Met 1-Gln 1066) was expressed, fused with a His tag at the C-terminus.
Source HEK293
Predicted N Terminal Met 1
AA Sequence Met 1-Gln 1066
Molecular Weight The recombinant human VCL consists of 1077 a.a. and has a calculated molecular mass of 118 kDa. The apparent molecular mass of rhVCL is approximately 115 kDa in SDS-PAGE under reducing conditions.
Purity >90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recently viewed