Recombinant Human URM1 Protein

Beta LifeScience SKU/CAT #: BL-4881PS
Recombinant Human URM1 Protein

Recombinant Human URM1 Protein

Beta LifeScience SKU/CAT #: BL-4881PS

Product Overview

Tag N/A
Host Species Human
Synonym Ubiquitin-related modifier 1 homolog, URM1, C9orf74, MGC2668, RP11-339B21.4.
Background URM1 is ubiquitin-related modifier 1 homolog protein which mainly functions in the post-translational modification of proteins via the urmylation pathway. Urm1 covalently binds to its E1 activating enzyme, Uba4p, to conjugate alkyl hydroperoxide reductase (Ahp1) as determined by studies with Saccharomyces cerevisiae. It has been theorized that this complex may then have a role in the oxidative-stress response in mammals.
Description URM1 expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 121a.a. (1-101 a.a.) and having a molecular weight of 13.5kDa.URM1 is fused to a 20a.a. His-tag at N-terminus and purified by unique purification methods.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MAAPLSVEVE FGGGAELLFD GIKKHRVTLP GQEEPWDIRN LLIWIKKNLL KERPELFIQG DSVRPGILVL INDADWELLG ELDYQLQDQD SVLFISTLHG G.
Purity >95.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The URM1 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 1mM DTT.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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