Recombinant Human UPK2 Protein
Beta LifeScience
SKU/CAT #: BL-4895PS
Recombinant Human UPK2 Protein
Beta LifeScience
SKU/CAT #: BL-4895PS
Catalog No.: BL-4895PS
Product Overview
| Tag | N/A |
| Host Species | Human |
| Synonym | Uroplakin-2, UP2, Uroplakin II, UPII, UPK2. |
| Background | Uroplakin 2 (UPK2) is one of the proteins of the highly urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is thought to strengthen the urothelium by preventing cell rupture during bladder distention. The UPK2 protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas. |
| Description | UPK2 Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 153a.a. (26-155 a.a) and having a molecular weight of 16.2kDa.UPK2 is fused to a 23a.a. His-tag at N-terminus and purified by unique purification methods. |
| Source | E.coli |
| AA Sequence | MGSSHHHHHH SSGLVPRGSH MGSDFNISSL SGLLSPALTE SLLVALPPCH LTGGNATLMV RRANDSKVVT SSFVVPPCRG RRELVSVVDS GAGFTVTRLS AYQVTNLVPG TKFYISYLVK KGTATESSRE IPMSTLPRRN MESIGLGMAR TGG. |
| Purity | >95.0% as determined by SDS-PAGE. |
| Endotoxin | <1.0 EU per μg by the LAL method. |
| Formulation | UPK2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2M UREA and 10% glycerol. |
| Stability | Recombinant protein is stable for 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
