Recombinant Human UNC5A Protein (ECD, His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4737
Recombinant Human UNC5A Protein (ECD, His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4737
Catalog No.: BLPSN-4737
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | NP_588610.2 |
| Synonym | UNC5H1 |
| Background | The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. In addition, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. |
| Description | A DNA sequence encoding the human UNC5A (NP_588610.2) (Met1-Tyr306) was expressed with a His tag at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Gln 26 |
| AA Sequence | Met1-Tyr306 |
| Molecular Weight | The recombinant human UNC5A consists 292 a.a. and predicts a molecular mass of 32.7 kDa. |
| Purity | >95% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
