Name: Recombinant Human ULBP2 Protein (His Tag)
Brand: Beta LifeScience
SKU: BLPSN-4730
Availability: InStock

Recombinant Human ULBP2 Protein (His Tag)

Catalog No.: BLPSN-4730

Product Overview

Tag	His
Host Species	Human
Accession	Q9BZM5
Synonym	ALCAN-alpha, N2DL2, NKG2DL2, RAET1H, UNQ463 / PRO791
Background	NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein which belongs to theMHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.
Description	A DNA sequence encoding the human ULBP2 (Q9BZM5) (Met 1-Ser 217), without the pro peptide, was fused with a His tag at the C-terminus.
Source	HEK293
Predicted N Terminal	Gly 26
AA Sequence	Met 1-Ser 217
Molecular Weight	The recombinant human ULBP2 consists of 203 a.a. and has a predicted molecular mass of 23.2 kDa. As a result of glycosylation, the apparent molecular mass of rh ULBP2 is approximately 33 kDa in SDS-PAGE under reducing conditions.
Purity	>97% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity	Please contact us for detailed information
Formulation	Lyophilized from sterile PBS, pH 7.4.
Stability	The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage	For Research Use Only
Storage	Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.