Recombinant Human ULBP2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4730

Recombinant Human ULBP2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4730
Catalog No.: BLPSN-4730
Product Overview
Tag | His |
Host Species | Human |
Accession | Q9BZM5 |
Synonym | ALCAN-alpha, N2DL2, NKG2DL2, RAET1H, UNQ463 / PRO791 |
Background | NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein which belongs to theMHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. |
Description | A DNA sequence encoding the human ULBP2 (Q9BZM5) (Met 1-Ser 217), without the pro peptide, was fused with a His tag at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Gly 26 |
AA Sequence | Met 1-Ser 217 |
Molecular Weight | The recombinant human ULBP2 consists of 203 a.a. and has a predicted molecular mass of 23.2 kDa. As a result of glycosylation, the apparent molecular mass of rh ULBP2 is approximately 33 kDa in SDS-PAGE under reducing conditions. |
Purity | >97% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |